ISTAC (also known as Systemic Integrative Treatment) was initially devised in 2017 by the Youth Untroubled team whilst working at the Brandon Centre, London. It is an adaptation of Multisystemic Therapy (MST), developed to better meet the needs of children and families with complex and multiple problems. The model has been commissioned by several local authorities and mental health trusts across London, and nationally by F-CAMHS. Youth Untroubled is currently commissioned to provide ISTAC in the south of England and is in the process of facilitating a national roll-out. 

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ISTAC is a community-based treatment programme, developed in accordance with NICE guidelines, to treat antisocial behaviour, chronic conduct disorders, and complex emotional and behavioural difficulties in children and young people. It is a cost-effective, evidence-based alternative to out-of-home placements and/or treatment (in foster care, secure accommodation, and CAMHS inpatient units).